Synthesis and Bleaching Activity of 1-Ethyl-and 1-Propyl-5-Substituted Imidazoles

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Synthesis and Bleaching Activity of 1-Ethyl- and 1 -Propy 1-5-Substituted Imidazoles

Twenty-eight 1-ethyland l-p ropyl-5-substitu ted imidazoles were synthesized and their bleaching activity was evaluated by using the lettuce seedling test. 5-Phenyl1-propylimidazole (1) caused distinct chlorosis, while none o f the com pounds with various alkenyl groups at the 5-position o f the im idazole ring showed this bleaching activity. In troduction o f a brom o, chloro, fluoro, methyl o...

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Synthesis and Leishmanicidal Activity of 1-[5-(5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl]-4-benzoylepiperazines

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Synthesis and Leishmanicidal Activity of 1-[5-(5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl]-4-benzoylepiperazines

A series of (5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl derivatives 6a–6e have been synthesized and screened for in vitro anti-leishmanial activity against the promastigote form of L. major. The structure of Schiff bases were confirmed by 1H NMR, IR. Screening results indicate that all of the designed and synthesized final compounds (6a-6e) significantly reduced the viability of promastigotes ...

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Design, Synthesis and Anti-Tubercular Activity of Novel 1, 4-Dihydropyrine-3, 5-Dicarboxamide Containing 4(5)-Chloro-2-Ethyl-5(4)-Imidazolyl Moiety

Current researches have showed that N3, N5-diaryl-2, 6-dimethyl -1, 4-dihydropyrine-3, 5- dicarboxamide analogues demonstrate notable anti-tubercular activity. In this study, Hantzsch condensation was used to design and synthesize new analogues of dihydropyridine (DHP). Different diary carboxamides were inserted at positions 3 and 5 of the DHP ring. 4(5)-chloro-2-ethyl-5(4)-imidazolyl moiety wa...

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ژورنال

عنوان ژورنال: Journal of the Faculty of Agriculture, Kyushu University

سال: 2001

ISSN: 0023-6152

DOI: 10.5109/24434